Trazodone is usually used at a dosage of 150 to 300 mg/day for the treatment of depression. ... The volume of distribution of trazodone is 0.8 to 1.5 L/kg. Trazodone is highly lipophilic. Metabolism. The metabolic pathways involved in the metabolism are not well-characterized. See more Trazodone, sold under many brand names, is an antidepressant medication. It is used to treat major depressive disorder, anxiety disorders, and difficulties with sleep. The medication is taken orally. Common side … See more Depression The primary use of trazodone is the treatment of unipolar major depression with or without anxiety. Data from open and double-blind trials suggest the antidepressant efficacy of trazodone is comparable to that of See more Trazodone is metabolized by several liver enzymes, including CYP3A4, CYP2D6, and CYP1A2. Its active metabolite meta-chlorophenylpiperazine (mCPP) is known to be formed by CYP3A4 and metabolized by CYP2D6. Inhibition or induction of the aforementioned … See more Trazodone is a triazolopyridine derivative and a phenylpiperazine that is structurally related to nefazodone and etoperidone, each of which are … See more Because of its lack of anticholinergic side effects, trazodone is especially useful in situations in which antimuscarinic effects are particularly … See more There are reported cases of high doses of trazodone precipitating serotonin syndrome. There are also reports of patients taking multiple SSRIs with trazodone and precipitating … See more Pharmacodynamics Trazodone is a mixed agonist and antagonist of various serotonin receptors, antagonist of adrenergic receptors, weak histamine H1 receptor antagonist, and weak serotonin reuptake inhibitor. More specifically, it is an … See more WebJun 2, 2015 · After 3 days, administration of tramadol was discontinued, and the trazodone dosage was increased (approx 7 mg/kg [3.2 mg/lb], PO, q 12 h) and maintained for at least 4 weeks.

Trazodone - Mechanism, Indication, Contraindications, …

WebAug 25, 2024 · Trazodone Dosage for Sleep. When prescribed for sleep, trazodone can be taken at several doses: The starting dose is usually 50 mg to 100 mg dose at bedtime. If … WebMAO inhibitors: Do not administer trazodone within 14 days of administering a MAO inhibitor when treating a psychiatric disorder. ... 6-12 years: 1.5-2 mg/kg/day PO in … sigma 105 money counter

Trazodone For Dogs Dosage Chart [Save Your Pup From Anxiety]

WebJan 11, 2024 · Initially 150 mg/day in divided doses after food or as a single dose on retiring. ... or in children who have ingested more than 150 mg trazodone within 1 hour of presentation. Alternatively, ... (0.10.3 mg/kg body weight) or lorazepam (4 mg in an adult and 0.05 mg/kg in a child). If these measures do not control the fits, ... WebTrazodone tablets come as 50mg, 100mg and 150mg strengths. Capsules come as 50mg and 100mg strengths. The liquid has either 10mg or 20mg of trazodone in every 1ml. For … the princess and the grilled cheese sandwich