Clofazimine drug interactions
WebDrug-induced neutropenia and agranulocytosis …agranulocytosis, namely clozapine and thionamides. The efficacy of prospectively monitoring the white blood cell count during clozapine therapy has been evaluated in two large series: After clozapine became available … Evaluation and management of treatment-resistant schizophrenia
Clofazimine drug interactions
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WebIn this case report the potential drug-drug interaction between cytochrome P450 (CYP) 3A4 substrates tezacaftor-ivacaftor and CYP3A4/5 inhibitor clofazimine is investigated in a patient with cystic fibrosis. Exposure to tezacaftor, ivacaftor and its metabolites was assessed by determination of the a … WebClofazimine Interactions There are 244 drugs known to interact with clofazimine, along with 2 disease interactions. Of the total drug interactions, 64 are major, 179 are moderate, and 1 is minor. Does clofazimine interact with my other drugs? Enter other …
WebApr 21, 2024 · Ocular: Conjunctival and corneal pigmentation due to clofazimine crystal deposits; dryness; burning; itching; irritation. Other: Discoloration of urine, feces, sputum, … WebAdverse reactions include discoloration of the skin, self-limiting gastrointestinal intolerance, severe and life-threatening abdominal pain and organ damage due to clofazimine …
WebAug 3, 2024 · This has been an inconsistent finding, 8 and formal drug–drug interaction studies are needed to investigate the effect of co-administration with lopinavir/ritonavir on clofazimine exposure and toxicity. Body composition explained our key finding of major sex differences in clofazimine plasma exposure. WebDrug Interactions between clofazimine and Orkambi. This report displays the potential drug interactions for the following 2 drugs: clofazimine; Orkambi (ivacaftor/lumacaftor) …
WebDrugs; Clofazimine; Clofazimine. Navigate to section. Indications and dose; Cautions; Interactions; Side-effects; Pregnancy; ... Related treatment summaries; Other drugs in class; Interactions. View interactions for clofazimine. Medicinal forms and pricing. There can be variation in the licensing of different medicines containing the same drug ...
WebApr 1, 2024 · Drug Interactions . Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. ... Clofazimine Clomipramine Clonixin Clopidogrel Clothiapine Clozapine Cocaine Codeine Crizotinib Cyclobenzaprine Dabigatran Etexilate Dabrafenib Dalteparin ... bobby fischer grave siteWebDose Adjustments. In erythema nodosum leprosum when corticosteroids are needed for the control of nerve injury or skin ulceration, clofazimine 100 to 200 mg orally once a day for … clinician intervention termsWebJul 20, 2024 · It is also proposed that clofazimine may disrupt cell membranes via interaction with intracellular redox cycling, leading to the generation of antimicrobial reactive oxygen species [ 21, 25 ]. It has also been hypothesized to inhibit cell replication by binding to the guanine bases of deoxyribonucleic acid [ 25 ]. … clinician leadershipWebThe clofazimine drug concentration we used in this experiment was 0.06 μg/mL, and the time points were set as 6 h, 16 h, and 52 h for the dosed group and the blank control group, respectively. ... The interaction between Rv1453 protein and Rv1455 double-stranded probe showed that with the increase in protein concentration, the migration band ... clinician impression of changeWebJul 23, 2024 · Drug-resistant tuberculosis (TB) is a growing public health problem. ... understanding such cross-resistance interactions is important for determining the drug combinations for treatments. ... bedaquiline (BDQ), linezolid (LZD), meropenem (MP), and clofazimine (CFZ); and two potential anti-TB drugs, i.e. clarithromycin (CM), and … clinician learningWebJan 1, 2024 · Pharmacokinetic interaction between bedaquiline and clofazimine in patients with drug-resistant tuberculosis Pharmacokinetic interaction between bedaquiline and clofazimine in patients with drug-resistant tuberculosis Int J Tuberc Lung Dis 2024 Jan 1;22 (1):26-29. doi: 10.5588/ijtld.17.0615. Epub 2024 Nov 16. Authors bobby fischer grandmaster at ageWebInteraction : Dapsone: May inhibit the anti-inflammatory activity of clofazimine have not been confirmed. If leprosy-associated inflammatory reactions develop in patients being treated with dapsone and clofazimine, it is still advisable to continue treatment with both drugs. Renal Dose : Dose in Renal Impairment GFR (mL/min) bobby fischer greatest chess player ever